Allay Therapeutics: A Site-Specific Drug Implant Treats Postsurgical Pain

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With a bioresorbable drug-eluting implant, Allay Therapeutics hopes to deliver the best level of pain relief for each phase of postsurgical recovery, starting with total knee replacement. Here, severe pain often interferes with the rehabilitation required for good outcomes.

Total knee arthroplasty is often described as a brutal surgery in terms of the pain patients experience directly after the surgery and during the rehabilitation phase. Indeed, pain is a factor that compromises outcomes, because in the days following surgery when patients need to be up and moving to avoid the formation of scar tissue in the knee, many don’t get up off the couch because their pain is so intense.


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